Why IVIG as a supportive care treatment?

Incorporating intravenous immunoglobulin (IVIG) into a chemotherapy regimen as a supportive care treatment holds the potential to transform the cancer treatment experience by protecting patients from many of the therapy's most damaging side effects.

IVIG is known for its powerful immunomodulatory and anti-inflammatory properties, which may help preserve nerve function and reduce the risk or severity of chemotherapy-induced peripheral neuropathy--common and often permanent complication. It may also support cognitive function by reducing inflammation in the brain, potentially protecting against "chemo brain", the memory and concentration difficulties many patients face during and after treatment. IVIG can aid in preserving cardiac function, especially important for patients receiving cardiotoxic drugs, and support bone marrow recovery, helping to maintain healthy blood cell counts and immune defenses. By strengthening the immune system, IVIG may reduce the risk of life-threatening infections when white blood cell counts are low and has the potential to help reduce the risk of metastasis. Importantly, these benefits come without compromising the cancer-fighting effects of chemotherapy. When used between rounds of treatment, IVIG may help patients maintain strength, recover more quickly, and avoid treatment delays--ultimately improving not just survival, but quality of life throughout the cancer journey.

To bring this promising treatment to the patients who need it most, we must first prove its efficacy. Currently, there are no clinical trials confirming that IVIG can be safely used alongside chemotherapy without diminishing its cancer-fighting power. At Hope Between Rounds, we are committed to changing that--with your support. Our mission is to fund the clinical research needed to demonstrate that IVIG can protect the body during treatment without interfering with the effectiveness of chemotherapy. Together, we can help redefine cancer care--one where survival doesn't come at the cost of long-term suffering.